We support any technically feasible research idea, on any rare disease topic.
Prior to 2022, we supported any healthcare topic. As such, some of the projects described below are about common (not rare) conditions.
External experts and national research groups are invited to contribute to project development. This multifaceted approach enables competitive applications to public funders, research charities or industry partners. If funding is achieved, projects become active and as autonomous as possible to reallocate PLRH resources to new proposals.
Once the research question is established, clinical trialists and statisticians conduct a preliminary assessment. The PLRH ethos is that, if a proposal is feasible and addresses an unmet need, it should be supported. Feasible ideas might require extensive background and design work to prepare for a funding application.
Funding calls for healthcare research are incredibly competitive; for example, less than 30% of all NIHR funding applications are successful. We think it's important to keep a record of our unsuccessful applications in case we can re-visit or build a new collaboration in the future.